Regenstrief Institute, Centerstone Research Institute, South Bend Memorial Hospital, Marshfield Clinic and Wake Forest School of Medicine receive grant to reduce healthcare costs and improve patient care
Bloomington, IN – Indiana University (IU) Bloomington, Regenstrief Institute, Centerstone Research Institute (CRI), South Bend Memorial Hospital, Marshfield Clinic and Wake Forest School of Medicine have joined forces to reduce healthcare costs and improve patient outcomes. The organizations are launching a new collaborative research project aimed at advancing the use of artificial intelligence in healthcare decision support. Made possible by a three-year, $686,000 grant from the National Science Foundation and National Institutes of Health, the project will begin January 1, 2014.
“We’re excited to partner with Regenstrief Institute, CRI, South Bend Memorial, Marshfield Clinic and Wake Forest on this project,” said Kris Hauser, IU Bloomington assistant professor in the School of Informatics and Computing. “The results of this research will provide tremendous insight into how new technology can positively influence healthcare costs and practices.”
The research team will study two state-of-the-art artificial intelligence analytical methods—statistical relational models and partially observable Markov decision processes—with the aim of advancing their use in healthcare. Statistical relational learning is a subdiscipline of artificial intelligence that uses models to describe the uncertainty of a data set and its complex, relational properties. The partially observable Markov decision process is a general framework that yields optimal actions for a real-world sequential decision process. The grant will allow the team to combine these techniques into one robust clinical decision support tool that can recommend best-practice action plans and compare optimal decisions against current clinical practices.
“Recent studies have demonstrated the immense value leveraging healthcare data can have on providers’ ability to offer more efficient and effective care,” said Regenstrief investigator and associate professor of medicine Dr. Shaun Grannis. “This grant will allow us to combine two proven AI-based clinical decision support approaches to create a more powerful, more accurate tool.”
The resulting tool will integrate billions of electronic health record data points with expert recommendations to give clinicians a better understanding of treatment outcomes, costs and best practices. In addition, the project will provide the groundwork for future research in decision support presentation and integration with clinical workflow.
“Integrating advanced analytics into everyday practice brings us one step closer to a better healthcare system,” said Tom Doub, PhD, chief executive officer at CRI. “Through collaborations like this one that bring together so many diverse experts in healthcare, information technology and research, we have great opportunity to transform healthcare delivery.”
Indiana University Bloomington will lead research efforts with Regenstrief Institute and CRI providing key support. Researchers from these organizations will look to develop the progression models as well as the clinical decision support tool. South Bend Memorial, Marshfield Clinic and Wake Forest will provide consultation based on their expertise to input clinical knowledge into the AI system. Consultants also will help evaluate generality and validity of the research and tools in three separate clinical domains.
The research team includes:
- Kris Hauser, PhD, Indiana University Bloomington – Principal Investigator
- Sriraam Natarajan, PhD, Indiana University Bloomington – Co-Principal Investigator
- Shaun Grannis, MD, MSc, Regenstrief Institute – Co-Principal Investigator
- Jon Duke, MD, Regenstrief Institute – Collaborator
- Casey Bennett, Centerstone Research Institute – Key Personnel
- Raman Mitra, MD, South Bend Memorial Hospital – Consultant
- Michael Caldwell, MD, Marshfield Clinic – Consultant
- Jeffrey Carr, MD, MSc, Wake Forest School of Medicine – Consultant
About Indiana University
IU Bloomington is the flagship residential, research-intensive campus of Indiana University. Its academic excellence is grounded in the humanities, arts and sciences, and a range of highly ranked professional programs. Founded in 1820, the campus serves more than 42,000 undergraduate and graduate students pursuing degrees in more than 300 disciplines. Widely recognized for its global and international programs, outstanding technology and historic limestone campus, IU Bloomington serves as a global gateway for students and faculty members pursuing issues of worldwide significance.
About Regenstrief Institute
The Regenstrief Institute Inc. is a distinguished medical research organization dedicated to improving the quality of health care and is the home of internationally recognized centers of excellence in medical and public health informatics, aging, and health services and health systems research. Institute investigators are faculty members of the IU School of Medicine, other schools at Indiana University-Purdue University Indianapolis, or Purdue University.
About Centerstone Research Institute
Centerstone Research Institute (CRI) is a not-for-profit organization dedicated to improving the quality and effectiveness of care for those with mental health and addiction disorders. CRI provides research, analytics and evaluation services that help bridge the gap between the scientific discovery of effective treatments and the implementation of these treatments into standard clinical practice. CRI is funded through contracts, grants, foundations and individual donors who share the organization’s commitment to bridging the gap between science and service.